Hi @JasonC,
I assume you are talking about the custom metadata fields. There no way to force filling these when creating an entry from KMC, however, if your users upload entries from an external system using the API, you can obviously do that during the upload submission stage.
You can also set moderation in KMC so if your users are uploading from Kaltura Media Space, for example, it will not become public until someone who has the right privileges goes onto KMC and approves them.